• Study Dir III Metabolism

    Job Location(s) US-WI-Madison
    Job Number
    Job Category
    Scientific Advanced Degree
    Position Type
  • Job Overview

    We are looking to add a Staff Scientist – Metabolite ID and Profiling to our Drug Metabolism team. In this role, you will perform day-to-day technical management of studies. Other job duties would include the following:
    • Responsible for the design, conduct and reporting of studies to meet scientific, regulatory and client requirements. 
    • Review technical validity of projects and results 
    • Maintain positive control over timing and scheduling issues related to the study process. 
    • Identification of drug metabolites using liquid chromatography-tandem mass spectrometry, NMR, and other analytical methodologies. 
    • Evaluates data for report preparation and experiment modification, as applicable and writes comprehensive reports. 
    • Quantitative analysis using LC-MS/MS. 
    • Implements new techniques and instrumentation to improve technical operations. 
    • Accepts leadership role in troubleshooting and solving challenging bioanalytical and biotransformation problems. 
    • Prepares scientific reports that document the analytical results and interpretation for the identification of drug metabolites. 
    • Performs scientific mentoring activities (e.g.; training study specific techniques, assisting with complex analytical work/problem solving, and presenting technique seminars). 
    • Assesses interest and feasibility of research projects requiring a high degree of creativity and technical organization. 
    • Conducts both fundamental and general application studies in the areas of bioanalytical chemistry and biotransformation. 
    • Project management responsibilities, including: client interaction. 
    • Authors scientific papers, which are published in peer reviewed journals, and presented in scientific meetings. 

    With two state-of-the-art metabolism laboratories in Madison, Wisconsin, and Harrogate, UK, Covance has helped hundreds of pharmaceutical and biotechnology companies select compounds to progress into development. Covance provides a comprehensive range of ADME services to support drug discovery and development programs. At Covance, you can make a difference by helping to deliver life-saving and life-enhancing medicines to people around the world. Our commitment to this mission has resulted in Covance’s impressive history of company stability and growth. We’ve achieved these results by fostering a work environment that encourages, develops and leverages our team’s capabilities.



    • PhD or equivalent, or BSc degree in an appropriate scientific discipline, with research experience in drug development or similar field
    • Experience of a range of techniques/approaches relevant to the department and/or unique expertise for a specific scientific service
    • Experience in coaching, mentoring, and supervision
    • Experience of requirements for working within a GLP, GCP and GMP (as appropriate) environment
    • Skilled data interpretation and report writing experience
    • Working knowledge of software (eg, MS Word, Excel), specialty applications (eg, Analyst, Sigmaplot, WinNonLin Phoenix), and general IT skills


    Minimum Required:

    • Full understanding of the drug development process, regulatory requirements and the scientific techniques of Metabolism studies required.
    • Extensive experience of client management and technical expertise in the relevant business line.
    • Fully competent in a Study Director role or equivalent and have developed skills and competencies in the relevant study types.


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